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Srinivas, Leela
- Antioxidant Activity of Indian Medicinal Plants
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1 Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagara-571 448, Mandya District, Karnataka, IN
1 Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagara-571 448, Mandya District, Karnataka, IN
Source
The Indian Journal of Nutrition and Dietetics, Vol 51, No 1 (2014), Pagination: 39-52Abstract
In oxidative stress, reactive oxygen species (ROS) such as superoxide (O2* -, OOH*), hydroxyl (OH*) and peroxyl (ROO*) radicals are generated. The ROS play an important role in several human diseases such as cancer, neurodegenerative disorders, cardiovascular diseases, atherosclerosis, cataracts and inflammation . The present paper deals with a preliminary screening of herbal edible plants; Chillies (Capsicum annum), curry leaves (Murrya kaneigi), ginger (Zingiber officinals), sacred basil or Tulasi (Ocimum sanctum), fennel seeds or Sompu (Foeniculum vulgare) and Turmeric (Curcuma longa). Several ethanobotanical uses have been described like antidiabetic, antiulcer, antitumor, antimicrobial, analgesic, anti-inflammatory, antiallergic, and other activities to these plants. The antioxidant activity was further confirmed by diene-triene-tetrane conjugation for different plant extracts as a sensitive index of lipid peroxidation.The different plant extracts were observed to inhibit dienetriene- tetrane conjugation. Turmeric extract was shown to inhibit conjugation at all stages effectively than other extracts and the inhibition was comparable to standards BHA and curcumin.Keywords
Reactive Oxygen Species, Neurodegenerative Disorders, Pharmacotherapeutic.
References
- Naskar, S., Mazumder, U.K., Pramanik, G., Bala, A., Haldar, P.K., Islam, A. and Gupta, M. Comparative in vitro antioxidant activity of different parts of Cocos nucifera (Linn.) On reactive oxygen and nitrogen species. Intern. J.Pharm. Pharmaceut. Sci., 2011, 3(3), 104-107.
- Markoviæ, J.M.D., Markoviæ, Z. S., Pašti, I.A., Brdariæ, T.P., Popoviæ-Bijeliæ, A. and Mojoviæ, M. A joint application of spectroscopic, electrochemical and theoretical approaches in evaluation of the radical scavenging activity of 3-OH flavones and their iron complexes towards different radical species. Dalt. Transs., 2012, 41, 7295-7303.
- He, S. and Yan, X. From resveratrol to its derivatives: New sources of natural antioxidant. Curr. Med. Chem., 2013, 20, 1005-1017.
- Halliwell, B. Free radicals, antioxidants and human diseases; Curiosity, cause, or consequences ? Lancet, 1994, 334, 721-724.
- Madian, Ashraf G. and Fred E. Regnier. Proteomic identification of carbonylated proteins and their oxidation sites. J.Proteo. Res., 2010, 9.8, 3766-3780.
- Cicerale, S., Lucas, L.J. and Keast, R.S.J. Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil. Curr. Opin.Biotechnol., 2012, 23, 129-135.
- Chand, T., Bhandari, A., Kumawat, B.K., Sharma, A., Pareek, A. and Bansal, V. K. In vitro antioxidant activity of aqueous extract of seeds of Cucumis callosus (Rottl.) Cogn. Der Pharmacia Lettre, 2012, 4, 840-844.
- Liu, C.Y., Lin, Y.C., Deng, J.S., Liao, J.C., Peng, W.H. and Huang, G.J. Antioxidant, antiinflammatory and antiproliferative activities of Taxillus sutchuenensis. Amer.J.Chinese Med., 2012, 40, 335-348.
- Loganayaki, N., Suganya, N. and Manian, S. Evaluation of edible flowers of agathi (Sesbania grandiflora L. Fabaceae) for in vivo anti-inflammatory and analgesic, and in vitro antioxidant potential. Fd. Sci. Biotechnol., 2012, 21, 509-517.
- Hema, T.A., Arya, A.S., Suseelan, S., Celestinal, R.J. and Divya, P.V. Antimicrobial activity of five south indian medicinal plants against clinical pathogens. Intern. J. Pharm. Bio Sci., 2013, 4 , 70-80.
- Bhavanishanker, T.N., Shanth, N.V., Ramesh, H.P., Indira, A.S. and Sreeinivasmurthy V. Toxicity studies on turmeric (Curcuma Longa): acute toxicity studies in rats, guinea pigs and monkeys. Ind. J. Exptl. Biol., 1980, 18, 73.
- Ali, B.H., Blunden, G., Tanira, M.O. and Nemmar, A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Fd. Chem. Toxicol., 2008, 46, 409-420.
- Krishnaswamy, K. Traditional Indian spices and their health significance. Asia Pacific J. Clin. Nutr., 2008, 17, 265-268.
- Witschi, H.P. Enhancement of tumor formation in mouse lung by dietary butylated hydroxytoluene (BHT). Toxicol., 1981, 21, 95-104.
- Barros, L., Cabrita, L., Boas, M.V., Carvalho, A.M. and Ferreira, I.C. Chemical, biochemical and electrochemical assays to evaluate phytochemicals and antioxidant activity of wild plants. Fd. Chem., 2011, 127, 1600-1608.
- You, L., Zhao, M., Regenstein, J.M. and Ren, J. In vitro antioxidant activity and in vivo anti-fatigue effect of loach (Misgurnus anguillicaudatus) peptides prepared by papain digestion. Fd. Chem., 2011, 124, 188-194.
- Krishnaiah, D., Sarbatly, R. and Nithyanandam, R. A review of the antioxidant potential of medicinal plant species. Fd. Bioprod. Proc., 2011, 89, 217-233.
- Potdar, B.M., Usman, M.R.M., Salgar, S.D., Sali LP. and Hameed, M.A.M. A nove. Natural premeatioin enhancer for famciclovir cream. Int. J. Int. Sci. Inn. Technol., Sec B, 2012, 1, 15- 18.
- Hurrell and Puentes, Medicinal and aromatic species of Asteraceae commercialized in the conurbation Buenos Aires-La Plata (Argentina). Ethnobio. Conserv., 2013, 2, 1-40 20. Dhiman, A., Nanda, A. and Ahmad, S.A. Quest for staunch effects of flavonoids: Utopian protection against hepatic ailments. Arabian J. Chem., 2012, 1-11.
- Colombo, M.L., Pinorini-Godly, M.T. and Conti, A. Botany and pharmacognosy of the Cacao tree. In Chocolate and Health, Springer Milan. 2012, 41-62).
- Ningappa, M.B., Dinesha, R. and Srinivas, L. Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Fd. Chem, 2008, 106, 720-728.
- Charles, D.J. Fenugreek. In: Antioxidant Properties of Spices, Herbs and Other Sources. Springer New York., 2013, 295, 303.
- Kamatou, G.P. Vermaak, I. and Viljoen, A.M. Eugenol from the remote Maluku islands to the international market place: A review of a remarkable and versatile molecule. Mol., 2012, 17, 6953-6981.
- Hussain, S.A., Panjagari, N.R., Singh, R.R.B. and Patil, G.R. Potential herbs and herbal nutraceuticals: food applications and their interactions with food components. Crit. Rev.Fd. Sci.Nutr., 2013 (In press).
- Kubra, I.R. and Rao, L.J.M. An impression on current developments in the technology, chemistry and biological activities of ginger (Zingiber officinale Roscoe). Crit. Rev. Fd. Sci.Nutr., 2013, 52, 651-688.
- Kadam, M.L., Hashmi, S.I. and Kale, R.V. Studies on extraction of ginger oil and its microencapsulation. Carpathian J. Fd. Sci. Technol., 2010, 2, 30-39.
- Srinivas, T.L., Lakshmi, S.M., Shama, S.N., Reddy, G.K. and Prasanna, K.R. Medicinal plants as anti-ulcer agents. J.Pharma. Phytochem., 2013, 2, 91-97.
- Joseph, B. and Nair, V.M., Ethanopharmacological and phytochemical aspects of Ocimum sanctum Linn-The elixir of life. Brit. J.Pharmaceut. Res., 2013, 3.
- Pandey, A.K., Singh, P. and Tripathi, N.N. Chemistry and bioactivities of essential oils of some Ocimum species: an overview. J.Coast. Life Med., 2013, 1, 192-205
- Manonmani, R. Antibacterial evaluation and phytochemical analysis of the seed extract of Foeniculum vulgare Mill. J. Pharm. Res., 2011, 4.
- Rather, M.A., Dar, B.A., Sofi, S.N., Bhat, B.A. and Qurishi, M.A. Foeniculum vulgare: A comprehensive review of its traditional use, phytochemistry, pharmacology and safety. Arabian J. Chem ., 2012, In Press
- Chethankumar, M. and Srinivas, L. New biological activity against phospholipase A2 by turmerin, a protein from Curcuma longa L. Biol. Chem., 2008, 389, 299–303.
- Chethankumar, M., Anand, N. and Gangadhara, N.S. Isolation and characterization of an antioxidant protein from turmeric (Curcuma longa L.) peel waste: A new biological source. J.Pharm. Res., 2010, 3, 2659–2662.
- Dinesha, R. and Leela Srinivas, BGS-Haridrin – A new antioxidant glycoprotein of turmeric (Curcuma longa L)- Short communication. Ind.J. Nutr. Dietet, 2010, 47, 118
- Dinesha Ramadas and Leela Srinivas, Antioxidant effects of 28kDa protein from turmeric (Curcuma longa L), Asian J. Pharm. Clin. Res., 2011, 4, Suppl 1, 75-79.
- Shalini, V.K. and Srinivas L. Lipid peroxide induced DNA damage: protection by turmeric (Curcuma longa). Mol.Cell. Biochem., 1987, 77, 3–10.
- Smitha. S., Dhananjaya, B.L., Dinesha, R. and Leela Srinivas, Purification and characterization of a w34 kDa antioxidant protein (â-turmerin) from turmeric (Curcuma longa) waste grits. Biochem., 2009, 91,1156-1162.
- Srinivas, L., Shalini, V.K. and Shylaja, M. Turmerin: a water-soluble antioxidant peptide from turmeric (Curcuma longa). Arch. Biochem. Biophys., 1992, 292, 617–623.
- Fenton, H.J.H. Oxidation of tartaric acid in the presence of iron. J. Chem. Soc., 1984, 106, 899-910.
- Shalini, V.K., Luthra, M., Srinivas, L., Harinarayana Rao, S., Basti, S. and Reddy, N., Oxidative damage to the eye lens caused by cigarette smoke and fuel smoke condensates. Ind. J. Biochem.Biophys., 1994, 41, 261-266.
- Shimazaki, H., Ueta, N., Mowri, H.O. and Inoue, K. Formation of age pigment like florescent substances during peroxidation of lipids in model membranes. Biochimica et Biophysica acta, 1984, 792, 123-187.
- Dahle, L.K., Hill, E.G. and Holman, R.T. The thio barbituric acid reaction and the autooxidants of polyunsaturated fatty acid methyl esters. Arch. Biochem. Biophys., 1962, 98, 253-261.
- Dolge, J.T., Mitchell, C. and Hnanahan, D.J. The preparation and chemical characteristics of hemoglobin free ghost of human erythrocytes. Arch. Biochem. Biophys., 1963, 100, 119- 128.
- Stoffel, W. and Ahrens, E.H., Isolation and structure of the C16 unsaturated fatty acids in menhaden body oil. J.Amer.Chem. Soc., 1958, 80, 6604–6608.
- Bradford, M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem., 1976, 7, 248-254.
- Dubois, M., Gilles, K.A. and Hamilton, J.K., Rebers, P.A. and Smith, F. Colorimetric method for determination of sugar and related substances. Anal. Chem., 1956, 28, 899-910.
- Kujala, T.S., Oponen, J.M., Kloka, K.D. and Pihlaja, K. Phenolics and betacyanins in red beetischolar_main (Beta vulgaris) ischolar_main: Distribution and effect of cold storage on the contents of total phenolics and three individual compounds. J. Agric. Fd. Chem., 2000, 48, 5338-5342.
- Woisky, R. and Salatino, A. Analysis of propolis: some parameters and procedures for chemical quality control. J. Apicult. Res., 1998, 37, 99-105.
- Sadasivam, S. and Manickam, A. Identification of proteins. Biochemical Methods Second Ed. New Age International Publishers. 1997. 33. 184–186.
- Kivack, B. and Mert, T. Quantitative determination of a-tocopherol in Arbutus unedo by TLC densitometry and colorimetry. Fitoterapia, 2001, 72, 656-661.
- Yuan, J.P., Pend, J., Yin, K. and Wang, J.H. Potential health promoting effects of astaxathin: A high value carotenoid mostly from microalgae. Mol. Nutr. Fd. Res., 2011, 55, 150-165.
- Salmon, A.B., Richardson, A. and Pérez, V.I. Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging? Free Rad. Biol.Med., 2010. 48, 642-655.
- Rubió, L., Motilva, M.J. and Romero, M.P. Recent advances in biologically active compounds in herbs and spices: A review of the most effective antioxidant and anti-inflammatory active principles. Crit. Rev.Fd Sci. Nutr., 2012. (In press).
- Luo, Y., Recent advances of chitosan and its derivatives for novel applications in food science. J. Fd. Proc. Bev., 2013, 1, 13.
- Poljsak, B. and Milisav. L. The neglected significance of antioxidative stress. Oxi. Med. Cell. Longevity, 2012, 1-12.
- Poiroux-Gonord, F., Bidel, L.P., Fanciullino, A.L., Gautier, H., Lauri-Lopez, F. and Urban, L. Health benefits of vitamins and secondary metabolites of fruits and vegetables and prospects to increase their concentrations by agronomic approaches. J. Agric. Fd. Chem., 2010, 58, 12065-12082.
- Havsteen B.H. The biochemistry and medical significance of the flavonoids. Pharmacotherapy, 2002, 96, 67–72.
- Lam, R.Y., Woo, A.Y., Leung, P.S. and Cheng, C.H. Antioxidant actions of phenolic compounds found in dietary plants on low-density lipoprotein and erythrocytes in vitro. J.Amer. Coll. Nutr., 2007, 26, 233-242.
- Yang, C.S., Lambert, J.D. and Sang, S. Antioxidative and anti-carcinogenic activities of tea polyphenols. Arch. Toxicol., 2008. PMID: 19002670.
- Bovicelli, P. Radical-scavenging polyphenols: new strategies for their synthesis. J.Pharm. Pharmacol., 2007, 59, 1703-1710.
- Ningappa, M.B. and Srinivas, L. Purification and characterization of approximately 35 kDa antioxidant protein from curry leaves (Murraya koenigii L.). Toxicol. In Vitro, 2008, 22, 699- 709.
- Masuda, Y., Kikuzaki, H., Hisamoto, M. and Nakatani, N. Antioxidant properties of gingerol related compounds from ginger. Biofactors, 2004, 21, 293-296.
- Surh,Y.J. Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Fd. Chem. Toxicol., 2002, 40, 1091- 1097.
- Uma Devi, P., Ganasoundari, A., Vrinda, B., Srinivasan, K.K. and Unnikrishnan MK. Radiation protection by the ocimum flavonoids orientin and vicenin: mechanism of action. Rad. Res., 2000, 154, 455–460.
- Calíbrese, V., Bates, T.E., Mancuso, C., Cornelius, C., Ventimiglia, B., Cambria, M.T., Di Renzo, L., De Lorenzo, A. and Dinkova-Kostova, A.T. Curcumin and the cellular stress response in free radical-related diseases. Mol. Nutr.Fd. Res., 2008, 52, 1062-1073.
- Pari, L., Tewas, D. and Eckel, J. Role of curcumin in health and disease. Arch. Physiol.Biochem., 2008, 114, 127-149.
- Rice-Evans, C. and Burdon, R., Free radical-lipid interactions and their pathological consequences. Progr. Lipid Res., 1993, 32, 71-110.
- Halliwell, B. and Gutteridge, J.M. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol., 1990, 86, 1.
- Methi Leaves (Trigonella Foenum-Graecum): an Edible Rich Source of Lutein
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Authors
Affiliations
1 Adichunchanagiri Cancer Research Institute, B.C. Nagara-571 448, Nagamangala, Mandya Dist, Karnataka, IN
1 Adichunchanagiri Cancer Research Institute, B.C. Nagara-571 448, Nagamangala, Mandya Dist, Karnataka, IN
Source
The Indian Journal of Nutrition and Dietetics, Vol 47, No 4 (2010), Pagination: 167-170Abstract
Lutein is one of the important yellow carotenoids present in green leafy vegetables, yellow fruits, flowers and egg yolk. Human beings incapable of synthesizing lutein, have to depend on dietary sources for their requirements. The major carotenoids consumed in leafy vegetables are, P carotene, lycopene, lutein, violoxanthine, neoxanthine, cryptoxanthine and zeaxanthine'. Lutein is an important vision related hydroxy carotenoid, though has no pro-vitamin A activity and it is mainly accumulated in the macula of human eye.- BGS-Haridrin - A New Antioxidant Glycoprotein of Turmeric {Curcuma longa L)
Abstract Views :220 |
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Authors
R. Dinesha
1,
Leela Srinivas
1
Affiliations
1 Adichunchanagiri Cancer Research Centre, B.G Nagara -571 448, Nagamangala Taluk, Mandya District, Karnataka, IN
1 Adichunchanagiri Cancer Research Centre, B.G Nagara -571 448, Nagamangala Taluk, Mandya District, Karnataka, IN
Source
The Indian Journal of Nutrition and Dietetics, Vol 47, No 3 (2010), Pagination: 118-121Abstract
The Reactive Oxygen Species (ROS) can be harmful to cells, as it can cause oxidative damage to lipids, proteins and DNA. Standard antioxidants like Butyiated Hydroxy Anisole (BHA) and Butyiated Hydroxy Toulene (BHT) are effective but their toxicity and unwanted side effects rules out their human use. Turmerin, an antioxidant protein from Turmeric (Curcuma tonga) is known to be an effective antioxidant. Further search for antioxidant proteins of turmeric led to the discovery of a new giyco- protein antioxidant from boiling water extract of Turmeric (Curcuma tonga L).- Molecular Action of Vitamin A
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Authors
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1 Adichunchanagiri Biotechnology and Cancer Research Institute, B.G. Nagara - 571 448, Mandya District, Karnataka State, IN
1 Adichunchanagiri Biotechnology and Cancer Research Institute, B.G. Nagara - 571 448, Mandya District, Karnataka State, IN
Source
The Indian Journal of Nutrition and Dietetics, Vol 44, No 1 (2007), Pagination: 34-49Abstract
Vitamin A is an essential vitamin for growth, vision, and reproductive health, cellular differentiation and hence is an important vitamin. George Wald won the 1967 Nobel Prize in physiology or Medicine for his work with retina pigments (also called visual pigments), which led to the understanding of the role of vitamin A in vision. Preformed vitamin A, is the result of enzymic action on certain precursor compounds within the bodies of most vertebrate animals. These precursors of vitamin A comprise of quite a small proportion of a large group of compounds known as carotenoids.- Turmeric:The Indian Culinary Delight to the World
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1 Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagar a -571 448, Karnataka, IN
1 Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagar a -571 448, Karnataka, IN
Source
The Indian Journal of Nutrition and Dietetics, Vol 43, No 4 (2006), Pagination: 169-173Abstract
Turmeric (Curcuma longa) is an Indian spice, which has conquered the ethnic borders of South-East Asia as a culinary delight, which imparts a pleasant yellow colour always associated with Indian curry and imparts a pleasant smell to the recipe. Turmeric has been used through ages as part of our food as a preservative, as an additive and flavoring and coloring spice. It is found to have extensive use in auspicious ritual as a horbinger of glad tidings that mere touching and smearing of turmeric powder brings health benefits. That is why offering turmeric has been a widely used practice in India.- Is β-Carotene a Really Safe Antioxtoant ? An Appraisal
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Authors
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1 Adichunchanagiri Biotechnology and Cancer Research Institute, B.G. Nagara-571 448, Karnataka, IN
1 Adichunchanagiri Biotechnology and Cancer Research Institute, B.G. Nagara-571 448, Karnataka, IN